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Diffusion tensor imaging (DTI) had been proved to be a powerful tool to investigate the white matter integrity and visualize the neuronal axons in vivo. Most of the DTI-based studies mainly used the region-of-interest approach to investigate the abnormalities in areas of white matter tracts involved in mood regulation for patients with major depressive disorder (MDD). In this study, we explored the...
Major depressive disorder (MDD) is one of the most common affective disorders which ranks among the top causes of worldwide disease burden and disability. Recent studies suggested that MDD resulted in the functional connectivity alteration in the resting state brain networks, such as the emotional circuit and the default mode network (DMN). In addition to these emotion-relevant networks, some other...
Functional and structural neuroimaging studies of major depression disorder (MDD) have identified neurophysiologic abnormalities in multiple areas of the prefrontal cortex, the insula, the amygdale and the related parts of the striatum and thalamus. The functional knowledge of MDD was mainly obtained from the fMRI and PET studies, which reveal the local differences in blood oxygenation and metabolism...
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