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To test the in vitro antiviral activity of a crude tissue extract (CTE) from the earthworm Eisenia fetida, determine any effective components in the CTE, andelucidatepossiblemechanismsofaction. A CTE was made by homogenizing earthworms, followed by treatment with ammonium sulfate, then thermal denaturation. Inhibition of virus-induced cytopathic effect (CPE) was used to assess antiviral activity...
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