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The mutation operator of Biogeography-Based Optimization (BBO) makes a large advance for the diversity of the solution space. Generally speaking, the quality of a solution is closely related with the maximum mutation rate, which is always decided by experience. But for the different situations, the maximum mutation rate may be different. In this paper, we propose an Intelligent Mutation Operator of...
Hypertension is a very important risk factor for cardiac vascular disease. The previous studies showed that mitochondrial DNA mutations are associated with cardiovascular disease, including hypertension.In this study we did systematical analysis on the total 22 mitochondrial tRNAs and the clinical, genetic and molecular changes of 140 Chinese hypertension and 124 controls.This analysis identified...
Background Hypertension is a very common cardiovascular disease influenced by multiple genetic and environmental factors. More recently, there are some studies showed that mutations in mitochondrial DNA have been involved in its pathogenesis. In this study we did further investigations on this relationship. Methods Epidemiological research found a Han Chinese family with probable maternally transmitted...
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