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Background We report a method for detection of deep venous thrombosis with a technetium 99m-labeled peptide (DMP 444). The N-methyl-arginine-glycine-aspartic acid sequence on DMP 444 binds the glycoprotein IIb/IIIa receptor on activated platelets (inhibition constant [IC50] for fibrinogen binding=6 nmol/L). Methods DMP 444 (23 to 27 mCi) was injected into 11 patients with clinical suspicion of deep...
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