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Background
Progressive maturation of growth plate chondrocytes drives long bone growth during endochondral ossification. Signals from the epidermal growth factor receptor (EGFR), and from bone morphogenetic protein‐2 (BMP2), are required for normal chondrocyte maturation. Here, we investigated cross‐talk between EGFR and BMP2 signals in developing and adult growth plates.
Results
Using in vivo...