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Rash is a common epidermal growth factor receptor inhibitor–induced toxicity that can impair quality of life and treatment compliance.We sought to evaluate the efficacy of doxycycline in preventing erlotinib-induced rash (folliculitis) in patients with non-small-cell lung cancer.This open-label, randomized, prospective, phase II trial was conducted in 147 patients with locally advanced or metastatic...
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