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BACKGROUND
Cancer patients' symptom burden is commonly attributed to their cancer and treatment. Increasingly, cancer patients have many other chronic comorbid conditions. However, the degree to which these comorbid conditions may contribute to the patient‐reported symptom burden is unclear.
METHODS
This study explored the relations between the presence of comorbid conditions, the symptom experience...
BACKGROUNDAdvanced uterine leiomyosarcoma (ULMS) is an incurable disease. A significant percentage of cases of ULMS express estrogen and/or progesterone receptors (ER and/or PR). To the authors' knowledge, the role of estrogen suppression in disease management is not known.
METHODSThe authors performed a single‐arm phase 2 study of the aromatase inhibitor letrozole at a dose of 2.5 mg daily in patients...
BACKGROUND:The authors present long‐term results from a phase 2 study that assessed the efficacy of transrectal ultrasound hyperthermia plus radiation with or without androgen suppression for the treatment of locally advanced prostate cancer.
METHODS:Patients with clinical T2b‐T3bN0M0 disease (according to 1992 American Joint Committee on Cancer [AJCC] criteria) received radiation plus 2 transrectal...
BACKGROUND.This pilot randomized controlled trial (RCT) examined the clinical effects of 2 complementary (CAM) therapies, relaxation response therapy (RRT) and Reiki therapy, in men being treated with external beam radiotherapy (EBRx) for prostate cancer.
METHODS.Study participants were randomly assigned to weekly RRT, Reiki therapy twice weekly, or wait‐list control. Well‐validated instruments measured...
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