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Two mononuclear Schiff base complexes, [Zn(L)2] (1) and [Cu(L)2] (2) are synthesized involving bidentate N,O-donor ligand viz. 2-((E)-(3-methoxypropylimino)methyl)-6-methoxyphenol. Different spectroscopic tools like FTIR, UV–Vis, 1H NMR, 13C NMR etc. have been deployed to characterize complexes 1 and 2. Complex 1 has been analyzed using single crystal X-ray diffraction analysis method. Complexes 1...
Small heterocyclic molecules such as piperazine are potential pharmacotherapeutic agents and binding of these molecules to the hydrophobic pocket of capsid protein (CP) offers a new perspective for therapeutic intervention. Here, we report the crystal structure of CP from Aura virus (AVCP) in complex with piperazine at 2.2 Å resolution. Piperazine binds to the conserved hydrophobic pocket of CP where...
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