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Thep49 gene from baculovirusSpodoptera littoralis nucleopolyhedrovirus (SlNPV) was able to suppress apoptosis ofSf9 cells induced by virus infection. Ectopically expressed P49 protein had the capacity to inhibit the activity of Caspases, being the executioner of apoptosis. Digestion of P49 with human Caspase orBm-Caspase both yielded 10 and 40 kD fragments. Checking the sequence of P49, we found that...
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