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PLA2 enzyme hydrolyzes arachidonic acid, and other polyunsaturated fatty acids, from the sn‐2 position to release free arachidonic acid and a lysophospholipid. Previous studies reported that the PLA2 in invertebrate organisms participates in lipid signaling molecules like arachidonic acid release in immune‐associated tissues like hemocytes and fat bodies. In the present study, we cloned the BmPLA2...
Hedgehog (Hh) signals regulate invertebrate and vertebrate development, yet the role of the pathway in adipose development remains poorly understood. In this report, we found that Hh pathway components are expressed in the fat body of silkworm larvae. Functional analysis of these components in a BmN cell line model revealed that activation of the Hh gene stimulated transcription of Hh pathway components,...
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