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Since Ca 2+ -ATPase is a major determinant of calcium homeostasis in the lens, we examined the expression of Ca 2+ -ATPase by calcium. An immortalized human lens epithelial cell line, HLE B-3, was treated with thapsigargin to inhibit sarco/endoplasmic reticulum Ca 2+ -ATPase (SERCA) releasing calcium from intracellular stores. Isoforms of the plasma membrane Ca 2+ -ATPase...
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