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Purpose To investigate the short term effects of Doxycycline on MMP-2 and MMP-9. Methods Short term effects of Doxycycline (100 mg B.I.D.) on plasma levels of MMP-2 and MMP-9 were investigated in 20 healthy subjects; the effects of Doxy, Acetylsalicylic acid, Nitrates, and Enalapril on MMP-9 release from were assessed in isolated polymorphonuclear cells. Results In plasma, MMP-9 activity was reduced...
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