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BACKGROUND:The use of platinum‐based chemoradiation for esophageal cancer is routine, but it is unclear which class of cytotoxic are optimum. It was hypothesized that chemoradiotherapy with fluoropyrimidine, taxane, and camptothecin would have preserved or improved efficacy with no compromise in safety.
METHODS:Patients with histologically confirmed, resectable esophageal carcinoma were eligible...
To quantify the internal motion margin requirements for radiotherapy of tumors near the gastroesophageal junction (GEJ).Four-dimensional computed tomography (4DCT) scans were obtained for 25 patients with primary tumors located near the GEJ. The gross tumor volume (GTV) was manually contoured on the exhale-phase image from the 4DCT image set. A deformable image registration method was used to automatically...
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