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Purpose: The purpose of RTOG 97–12 was to determine the maximum tolerated dose (MTD) of thoracic radiation therapy (RT) with concurrent chemotherapy for patients with limited-stage small-cell lung cancer. Patients and Methods: Sixty-four patients received four cycles of cisplatin (60 mg/m 2 i.v.) and etoposide (120 mg/m 2 i.v. Days 1–3) (PE), with concurrent thoracic RT starting on...
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