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Summary We report the results of alendronate ingestion plus exercise in preventing the declines in bone mass and strength and elevated levels of urinary calcium and bone resorption in astronauts during 5.5 months of spaceflight. Introduction This investigation was an international collaboration between NASA and the JAXA space agencies to investigate the potential value of antiresorptive agents to...
To identify regions inside the hip experiencing the most significant bone loss due to long-duration spaceflight, we have employed inter-subject registration to integrate hip quantitative computed tomography (QCT) scans and constructed the pre- and post-flight composite hip models for 16 astronauts, who experienced 4-6 months of spaceflights on the International Space Station. To achieve this, we applied...
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