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The retinoids, a class of compounds related to vitamin A exert their effects via the retinoic acid (RA) receptors (RARs) and rexinoid receptors and play important roles in a number of physiological processes including vision, tissue maintenance, differentiation and embryonic development. RA, including all-trans RA (ATRA) and its stereoisomer 9-cis RA, have gained importance as chemotherapeutic agents...
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