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Mastoparan, a polypeptide known to activate heterotrimeric GTP-binding proteins, enhances the transport of Ca 2+ and K + across membranes. In the present study we investigated the influence of mastoparan on transepithelial resistance (TER) and on short circuit current (SCC) of the intestinal cell line T84. Mastoparan decreased the TER by 80% of baseline and induced a SCC of 8...
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