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Résumé: On sait que la cellule de Reed-Sternberg (cRS) dérive de cellules B activées post-germinales ayant échappé à l’apoptose. Les études sur cRS microdisséquées commencent à en définir le profil génomique. Le traitement actuel des formes limitées de LH est une courte chimiothérapie par ABVD, trois ou quatre cycles, suivie d’une radiothérapie «involved fieds». Les études en cours cherchent à réduire...
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