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AimmiR‐145 is a candidate tumor suppressor miRNA. However, it is unknown whether miR‐145 is involved in the invasion of hepatocellular carcinoma (HCC). Therefore, we aimed to explore the effect and mechanism of miR‐145 in the control of HCC cell invasion.
MethodsHCC cell invasion was evaluated by transwell assays after transfection with pre‐miR‐145 or anti‐miR‐145. A luciferase reporter assay was...
Background Fibulin-5 has been considered as a tumor suppressor through inhibiting tumor growth and invasion. Reduced expression of Fibulin-5 is frequently observed in various human cancers. In this study, we investigate the clinical significance of Fibulin-5 and its role in hepatocellular carcinoma (HCC) cell migration and invasion. Methods The expression of Fibulin-5 was evaluated by qRT-PCR and...
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