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Acute myeloid leukemias (AML) comprising approximately 15 % of pediatric leukemias account for 30 % of all leukemic deaths in children worldwide. The 5-year overall survival (OS) rate now reaches 60–65 % in Western Europe, North America, and the developed countries of Australasia due to risk-tailored chemotherapy and vigorous supportive care. According to data of the Childhood Cancer Registry of the...
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