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In article number 2000432, Tuomas P. J. Knowles and co‐workers demonstrate a simple microfluidic approach to produce spatially inhomogeneous protein microgels, using versatile crosslinking regimes and microfluidic dynamics under biocompatible conditions. The microgels are promising candidates for extracellular matrix analogues and tissue engineering scaffolds, which could open up new possibilities...
3D scaffolds in the form of hydrogels and microgels have allowed for more native cell‐culture systems to be developed relative to flat substrates. Native biological tissues are, however, usually spatially inhomogeneous and anisotropic, but regulating the spatial density of hydrogels at the microscale to mimic this inhomogeneity has been challenging to achieve. Moreover, the development of biocompatible...
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