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Background As with many anti-cancer drugs, the topoisomerase II inhibitor etoposide is considered safe for administration to women in the second and third trimesters of pregnancy, but assessment of effects on the developing fetus have been limited. The purpose of this research was to examine the effect of etoposide on germ cells in the developing ovary. Mouse ovary tissue culture was used as the experimental...
To evaluate a new fully automated assay measuring antimüllerian hormone (AMH; Roche Elecsys) against antral follicle count in women of reproductive age.Prospective cohort study.Hospital infertility clinics and academic centers.Four hundred fifty-one women aged 18 to 44 years, with regular menstrual cycles.None.AMH and antral follicle count (AFC) determined at a single visit on day 2–4 of the menstrual...
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