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Purpose: To answer the question whether a single fraction of radiotherapy that is considered more convenient to the patient is as effective as a dose of multiple fractions for palliation of painful bone metastases.Patients: 1171 patients were randomised to receive either 8Gy×1 (n=585) or 4Gy×6 (n=586). The primary tumour was in the breast in 39% of the patients, in the prostate in 23%, in the lung...
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