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Objective Patients undergoing chemoradiation for anal cancer are at risk of hematologic toxicity (HT) with rates of grade 3–4 HT as high as 60%. Studies have demonstrated a correlation between HT and the dose to pelvic bone marrow (PBM) as well as the positive emission topography (PET)-defined active pelvic bone marrow (APBM) spared. We hypothesize that the use of intensity modulated proton therapy...
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