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Induced pluripotent stem cells (iPSCs) are stem cells that can be artificially generated via “cellular reprogramming” using gene transduction in somatic cells. iPSCs have enormous potential in stem‐cell biology as they can give rise to numerous cell lineages, including the three germ layers. An evaluation of germ‐line competency by blastocyst injection or tetraploid complementation, however, is critical...
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