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Leukocyte function‐associated antigen‐1 (LFA‐1) and very late antigen‐4 (VLA‐4) integrins are essential for lymphocyte adhesion, trafficking and effector functions. Protein kinase D (PKD) has previously been implicated in lymphocyte integrin regulation through regulation of Rap1 activity. However, the true role of PKD in integrin regulation in primary lymphocytes has not previously been investigated...
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