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Background A strong association has been reported between HLA-B*1502 and severe cutaneous adverse drug reactions (CADRs) induced by carbamazepine (CBZ) in Han Chinese patients. However, some investigations showed that the HLA-B*1502 allele is not the universal marker for CADRs in European patients. Moreover, HLA-A*3101 was found to be associated with CBZ-induced hypersensitivity reactions among subjects...
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