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The aim of this study was to analyze pH-dependent permeability of cationic drugs in Caco-2 cell monolayers using the pKaflux method and to correlate the results with those obtained in PAMPA (parallel artificial membrane permeability assay). The pH-dependent permeability of verapamil and propranolol was studied in Caco-2 cell monolayers. The data were subsequently processed using software developed...
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