Search results for: Ji Young Park

Items from 1 to 20 out of 453 results

article

Preparation of h‐BN microspheres for nanocomposites with high through‐plane thermal conductivity

Hyung Jin Mun, Ji Young Park, Minseob Lim, Hong‐Baek Cho, more

Journal of the American Ceramic Society > 106 > 12 > 7240 - 7250

In recent times, electronics have been increasingly minimized, and hence, heat dissipation has become essential. Owing to its high thermal conductivity and superior electrical insulation, hexagonal‐boron nitride (h‐BN) has been regarded as an appropriate ceramic material to increase the thermal conductivity of polymer nanocomposites for effective heat dissipation. However, the poor through‐plane thermal...

article

ppb‐Level ethanol gas sensor of porous anodic aluminum oxide at room temperature

Ji Young Park, Jae‐Ho Yi, Yong‐Ho Choa

Journal of the American Ceramic Society > 106 > 12 > 7209 - 7217

Excessive ethanol in breath can be an indicator of alcoholism and a biomarker of liver disease. Herein, we present a novel porous aluminum anodic oxide (AAO)‐based chemi‐capacitive sensor that can detect ppb‐levels of ethanol gas at room temperature. The oxalic acid‐based porous AAO is an amorphous material contaminated with Al(OH)₃ and C₂O₄²⁻ ions (anion‐contamination), which react with adsorbed...

article

Li‐La‐Zr‐O Garnets with High Li‐Ion Conductivity and Air‐Stability by Microstructure‐Engineering (Adv. Funct. Mater. 35/2023)

Mohammad Nasir, Ji Young Park, Pilwon Heo, Kyoung Hwan Choi, more

Advanced Functional Materials > 33 > 35 > n/a - n/a

Two‐Step Sintering In article number 2303397, Hee Jung Park, Kyoung Hwan Choi, and co‐workers demonstrate the crucial role of grain growth behavior in determining the conductivity and air stability of solid electrolytes. A unique two‐step densification approach is presented, that enables the precise control over the microstructure of Li₇La₃Zr₂O₁₂ (LLZO), resulting in improved Li‐ion conductivity....

article

Li‐La‐Zr‐O Garnets with High Li‐Ion Conductivity and Air‐Stability by Microstructure‐Engineering

Mohammad Nasir, Ji Young Park, Pilwon Heo, Kyoung Hwan Choi, more

Advanced Functional Materials > 33 > 35 > n/a - n/a

Li₇La₃Zr₂O₁₂ (LLZO) solid electrolyte (SE) is a potential candidate for developing safe and economically all‐solid‐state batteries (ASSBs) owing to its high Li‐ion conductivity and electrochemical stability against lithium anodes. However, poor stability and significant reduction in conductivity when exposed to air, limit its practical use. Herein, a unique two‐step sintering approach is designed...

article

Neuroprotective effects of hydroponic ginseng fermented by Lactococcus lactis KC24 in oxidatively stressed SH‐SY5Y cells

Ji‐Young Park, Kee‐Tae Kim, Hyun‐Dong Paik

Journal of the Science of Food and Agriculture > 103 > 9 > 4413 - 4420

BACKGROUND Panax ginseng Meyer, a traditional herb in Asia, contains bioactive compounds such as polyphenolic compounds, flavonoids, and ginsenosides. Furthermore, fermentation with probiotics can promote the biofunctional activities of ginseng. This study's object was to investigate the neuroprotective effect of hydroponic ginseng against hydrogen peroxide (H₂O₂)‐induced cytotoxicity and its effect...

article

Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation

Yong Hoon Kim, Ae‐Young Her, Seung‐Woon Rha, Cheol Ung Choi, more

Catheterization and Cardiovascular Interventions > 101 > 6 > 1014 - 1027

Clinical outcomes after non‐ST‐segment‐elevation myocardial infarction (NSTEMI) in patients with (symptom‐to‐door time [SDT] ≥ 24 h) or without (SDT < 24 h) delayed hospitalization among patients with or without diabetes were compared. From the Korea Acute Myocardial Infarction Registry‐National Institute of Health, a total of 4517 patients with NSTEMI who underwent new‐generation drug‐eluting...

article

Simultaneous assessment of organophosphate flame retardants, plasticizers, trace metals, and house dust mite allergens in settled house dust

Donghyun Kim, Ji Young Park, Dong Hyun Lee, Jae‐Eun Lim, more

Indoor Air > 32 > 7 > n/a - n/a

Settled house dust (SHD) is a reservoir for various contaminants, including endocrine‐disrupting chemicals (EDCs), trace metals, and house dust mite allergens. This study aimed to characterize various chemical and biological contaminants in SHD and identify determinants governing the indoor contaminants. In total, 106 SHD samples were collected from 106 houses in Seoul and Gyeonggi Province, Korea,...

article

Structural, Electrical, and Optical Properties of ZnO Films Grown by Atomic Layer Deposition at Low Temperature

Ji-Young Park, Ye Bin Weon, Myeong Jun Jung, Byung Joon Choi

Archives of Metallurgy and Materials > 2022 > Vol. 67, iss. 4 > 1503--1506

Zinc oxide (ZnO) is a prominent n-type semiconductor material used in optoelectronic devices owing to the wide bandgap and transparency. The low-temperature growth of ZnO thin films expands diverse applications, such as growth on glass and organic materials, and it is also cost effective. However, the optical and electrical properties of ZnO films grown at low temperatures may be inferior owing to...

article

Effects of age and gender on the cytochrome P450 2D6 activity in a Korean population

Pil‐Whan Park, Yiel‐Hea Seo, Jeong‐Yeal Ahn, Kyoung‐Ah Kim, more

Journal of Clinical Pharmacy and Therapeutics > 46 > 6 > 1659 - 1664

What is known and objective Age and gender have been reported to play a crucial role in modulating the disposition of pharmacological agents, and to influence the activities of cytochrome P450 (CYP) 2D6, a drug‐metabolizing enzyme involved in the disposition of clinically used drugs. In the present study, the effects of age and gender on the CYP2D6 activity were evaluated using dextromethorphan as...

article

Association between asthma and clinical mortality/morbidity in COVID‐19 patients using clinical epidemiologic data from Korean Disease Control and Prevention

Hyo‐Geun Choi, Jee Hye Wee, So Young Kim, Joo‐Hee Kim, more

Allergy > 76 > 3 > 921 - 924

article

Advanced target‐specific probe‐based real‐time loop‐mediated isothermal amplification assay for the rapid and specific detection of porcine circovirus 3

Hye‐Ryung Kim, Da‐Rae Lim, Ha‐Gyeong Chae, Ji‐Young Park, more

Transboundary and Emerging Diseases > 67 > 6 > 2336 - 2344

Porcine circovirus type 3 (PCV3) is an emerging viral pathogen that has been identified in pigs with various clinical signs. For rapid and specific detection of PCV3, an advanced real‐time loop‐mediated isothermal amplification (rLAMP) assay that uses both assimilating probes and swarm primers were developed and evaluated in this study. The assay specifically amplified PCV3 DNA, but it did not amplify...

article

Clinical efficacy of intraoperative ultrasound for margin assessment in breast‐conserving surgery

Jeeyeon Lee, Ho Yong Park, Wan Wook Kim, Chan Sub Park, more

The Breast Journal > 26 > 11 > 2308 - 2311

article

Development of a liquid chromatography/tandem‐mass spectrometry assay for the simultaneous determination of teneligliptin and its active metabolite teneligliptin sulfoxide in human plasma

Jin‐Woo Park, Kyoung‐Ah Kim, Ji‐Young Park

Biomedical Chromatography > 34 > 2 > n/a - n/a

Teneligliptin is a recently developed dipeptidyl peptidase‐4 (DPP‐4) inhibitor for the treatment of type 2 diabetes mellitus. To study simultaneous pharmacokinetics of teneligliptin and its major active metabolite, teneligliptin sulfoxide in human plasma, we developed and validated a LC‐MS/MS method. The analytes were detected in the positive mode using multiple reaction monitoring (teneligliptin:...

article

Pharmacokinetic Analysis and Biomarker‐Assisted Safety Assessment of Acetaminophen in Combination With Ojeok‐san Compared With Acetaminophen Alone

Sang‐In Park, Ji‐Young Park, Ji Hyun Lee, Mun Su Park, more

The Journal of Clinical Pharmacology > 59 > 11 > 1485 - 1494

Acetaminophen and Ojeok‐san are both frequently used analgesics. In this study, we evaluated acetaminophen pharmacokinetics (PK) and changes in microRNA‐122 (miR‐122) levels after multiple dosing of acetaminophen with or without Ojeok‐san. An open‐label, 1‐sequence, 2‐period, 2‐treatment crossover study was conducted in 18 subjects. In period 1, 500 mg of acetaminophen was administered 3 times on...

article

Effects of Ketoconazole, a CYP4F2 Inhibitor, and CYP4F23* Genetic Polymorphism on Pharmacokinetics of Vitamin K₁

Jin‐Woo Park, Kyoung‐Ah Kim, Ji‐Young Park

The Journal of Clinical Pharmacology > 59 > 11 > 1453 - 1461

The objective of this study was to evaluate whether cytochrome P450 (CYP)4F2 is involved in the exposure of vitamin K₁ through a drug interaction study with ketoconazole, a CYP4F2 inhibitor, and a pharmacogenetic study with CYP4F2*3. Twenty‐one participants with different CYP4F2*3 polymorphisms were enrolled (8 for *1/*1, 7 for *1/*3, and 6 for *3/*3). All participants were treated twice daily for...

article

Pharmacokinetic and haemodynamic interactions between amlodipine and losartan in human beings

Jin‐Woo Park, Kyoung‐Ah Kim, Yong Il Kim, Ji‐Young Park

Basic & Clinical Pharmacology & Toxicology > 125 > 4 > 345 - 352

The combination of calcium channel blockers (CCB) and angiotensin receptor blockers (ARB) for the treatment of hypertension showed improved efficacy and safety. Amlodipine is mainly metabolized by cytochrome P450 (CYP) 3A4, whereas losartan is metabolized by CYP2C9 and CYP3A4. The potential pharmacokinetic interactions between amlodipine and losartan were assessed. An open‐label, three‐period, fixed‐sequence...

article

Effect of glimepiride on the pharmacokinetics of teneligliptin in healthy Korean subjects

Jin‐Woo Park, Kyoung‐Ah Kim, Yun Jung Choi, Soo Hyun Yoon, more

Journal of Clinical Pharmacy and Therapeutics > 44 > 5 > 720 - 725

What is known and objective Teneligliptin is a DPP‐4 inhibitor used for the treatment of type 2 diabetes mellitus, commonly prescribed in combination with glimepiride. Teneligliptin is metabolized by CYP3A4, and glimepiride might be partly metabolized by CYP3A4. The aim of the study was to investigate the possible effect of glimepiride on the pharmacokinetics of teneligliptin in healthy subjects...

article

Ultrasound-guided dual-localization for axillary nodes before and after neoadjuvant chemotherapy with clip and activated charcoal in breast cancer patients: a feasibility study

Won Hwa Kim, Hye Jung Kim, See Hyung Kim, Jin Hyang Jung, more

BMC Cancer > 2019 > 19 > 1 > 1-8

Background We report on our experience of ultrasound (US)-guided dual-localization for axillary nodes before and after neoadjuvant chemotherapy (NAC) with clip and activated charcoal to guide axillary surgery in breast cancer patients. Methods Between November 2017 and May 2018, a dual-localization procedure was performed under US guidance for the most suspicious axillary nodes noted at initial...

article

A Machine Learning-Based Approach for the Prediction of Acute Coronary Syndrome Requiring Revascularization

Yung-Kyun Noh, Ji Young Park, Byoung Geol Choi, Kee-Eung Kim, more

Journal of Medical Systems > 2019 > 43 > 8 > 1-8

The aim of this study is to predict acute coronary syndrome (ACS) requiring revascularization in those patients presenting early-stage angina-like symptom using machine learning algorithms. We obtained data from 2344 ACS patients, who required revascularization and from 3538 non-ACS patients. We analyzed 20 features that are relevant to ACS using standard algorithms, support vector machines and linear...

article

Thyroid transcription factor-1 as a prognostic indicator for stage IV lung adenocarcinoma with and without EGFR-sensitizing mutations

Ji Young Park, Seung Hun Jang, Hwan Il Kim, Joo-Hee Kim, more

BMC Cancer > 2019 > 19 > 1 > 1-8

Background Thyroid transcription factor (TTF)-1 expression is a diagnostic marker and a good prognostic indicator for lung adenocarcinoma. However, its good prognostic ability might be due to epidermal growth factor receptor (EGFR)-sensitizing mutations as shown by the positive correlation between TTF-1 expression and EGFR mutations. We explored the prognostic impact of TTF-1 expression according...

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Search results for: Ji Young Park

Preparation of h‐BN microspheres for nanocomposites with high through‐plane thermal conductivity

ppb‐Level ethanol gas sensor of porous anodic aluminum oxide at room temperature

Li‐La‐Zr‐O Garnets with High Li‐Ion Conductivity and Air‐Stability by Microstructure‐Engineering (Adv. Funct. Mater. 35/2023)

Li‐La‐Zr‐O Garnets with High Li‐Ion Conductivity and Air‐Stability by Microstructure‐Engineering

Neuroprotective effects of hydroponic ginseng fermented by Lactococcus lactis KC24 in oxidatively stressed SH‐SY5Y cells

Effects of delayed hospitalization on the 3‐year clinical outcomes of patients with or without diabetes who had non‐ST‐segment‐elevation myocardial infarction and underwent new‐generation drug‐eluting stent implantation

Simultaneous assessment of organophosphate flame retardants, plasticizers, trace metals, and house dust mite allergens in settled house dust

Structural, Electrical, and Optical Properties of ZnO Films Grown by Atomic Layer Deposition at Low Temperature

Effects of age and gender on the cytochrome P450 2D6 activity in a Korean population

Association between asthma and clinical mortality/morbidity in COVID‐19 patients using clinical epidemiologic data from Korean Disease Control and Prevention

Advanced target‐specific probe‐based real‐time loop‐mediated isothermal amplification assay for the rapid and specific detection of porcine circovirus 3

Clinical efficacy of intraoperative ultrasound for margin assessment in breast‐conserving surgery

Development of a liquid chromatography/tandem‐mass spectrometry assay for the simultaneous determination of teneligliptin and its active metabolite teneligliptin sulfoxide in human plasma

Pharmacokinetic Analysis and Biomarker‐Assisted Safety Assessment of Acetaminophen in Combination With Ojeok‐san Compared With Acetaminophen Alone

Effects of Ketoconazole, a CYP4F2 Inhibitor, and CYP4F23* Genetic Polymorphism on Pharmacokinetics of Vitamin K₁

Pharmacokinetic and haemodynamic interactions between amlodipine and losartan in human beings

Effect of glimepiride on the pharmacokinetics of teneligliptin in healthy Korean subjects

Ultrasound-guided dual-localization for axillary nodes before and after neoadjuvant chemotherapy with clip and activated charcoal in breast cancer patients: a feasibility study

A Machine Learning-Based Approach for the Prediction of Acute Coronary Syndrome Requiring Revascularization

Thyroid transcription factor-1 as a prognostic indicator for stage IV lung adenocarcinoma with and without EGFR-sensitizing mutations

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