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The quantitative structure-activity relationship of 2-(arylimino)oxazolidines (AIOs) and 2-(substituted benzylamino)-2-oxazolines (SBOs) in stimulating adenylate cyclase prepared from thoracic nerve cords of the American cockroachPeriplaneta americanaL. was examined using parameters calculated by a molecular orbital procedure. The more hydrophobic and the smaller the highest occupied molecular orbital...
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