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A mixture of dipeptides (DP) have been proposed as an alternative (to glucose and amino acids, AA) osmotic agent in peritoneal dialysis (PD) solutions. The following solutions were used: (1) the amino acids (AA) solution containing leucine, valine, lysine, isoleucine, threonine, phenylalanine and histidine (tyrosine was omitted because of its poor solubility), (2) the dipeptide (DP) solution containing...
Dipeptide-based peritoneal dialysis solutions may have potential advantages compared with the gIucose or amino acid-based solutions. DwelI studies in rats were performed during 4 hours with dipeptide solutions containing 5 dipeptides (Gly-His, Ala-Tyr, Thr-Leu, Ser-Phe, Val-Lys), 8 or 16 mmol/l of each dipeptide (low or high dipeptide group). DwelI studies were also performed with a 1.1% amino acid...
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