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Background. Ghrelin, a newly discovered hormone is involved mainly in the regulation of body energy homeostasis. It has also been proved that ghrelin affects many other processes including the control of the hypothalamo-pituitary-gonadal axis in vertebrates. Ghrelin interacts also with other peptides and neurotransmitters, which are involved in gonadotropin release, such as endogenous opioid peptides...
The effects of naltrexone on the in vitro luteinizing hormone (LH) secretion from whole pituitary glands as well as from dispersed pituitary cells of common carp (Cyprinus carpio L.)in primary cell culture were studied. The perifusion of whole pituitary glands with naltrexone at a concentration of 10⁻⁴ M caused a significant increase of LH secretion compared to the control. This finding suggests that...
The present study compare oral and rectal delivery routes of a salmonid gonadotropin releasing hormone analogue (sGnRH-a)+dopamine D 2 -receptor antagonist, pimozide (Pim), with parenteral administration. In addition, the effect of co-administration of absorption enhancers and peptidase inhibitors were evaluated. Responsiveness to the treatments was examined using GtH II release. Ten micrograms...
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