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Built upon the hypergeometric distribution, the Fisher Exact Test score (FETS) and its variants offer a natural way of quantifying the level of TF binding site (TFBS) motif enrichment, and have been chosen as the objective functions of several widely used discriminant motif discovery methods, such as HOMER and DREME. In spite of its popularity and efficacy, FETS is non-smooth and non-differentiable,...
Cluster validation techniques are essential tools within cluster analysis, helpful to the interpretation of clustering results. In this study, the validation ability of Dunn's index in gene clustering was investigated with public gene expression datasets clustered by hierarchical clustering, K-means and Self-organizing maps. It was made clear that Dunn's index would give misleading validity results...
Scientific workflow is becoming an important paradigm for scientific computations and collaborations. Provenance information plays an important role to reproduce data and prove the soundness of result for scientific workflow. The provenance information can be collected by keeping a complete trace of the workflow execution. In this paper, we give a high level Workflow Net model based on many-sorted...
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