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Purpose: It is known that the medication used to induce anesthesia alters resting shape of red blood cells but their ability to deform to carry nutrients to microvessels is not well established. Aim of this study is to analyse the effect of local anesthetic on the deformability of human red blood cells in vitro.Methods: Red blood cells suspended in desired concentrations of local anesthetic (Procaine)...
Purpose: To characterize the regulatory elements dictating the tissue-specific expression of the Interleukin-8 (IL-8) receptor A and B genes.Methods: Northern blot analysis and IL-8 induced calcium mobilization were used to identify a cell line that proliferates continuously in culture and expresses the IL-8 receptor genes. 5[prime ]-sequences of the IL-8 receptor genes A and B were cloned upstream...
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