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Aims: Oral administration of probiotics has been known to improve inflammatory responses against infectious diseases. Here, we describe the inhibitory effect of oral intake of heat‐killed Lactobacillus pentosus strain b240 (b240) on pneumococcal pneumonia in a murine experimental model.
Method and Results: The mice treated with oral b240 for 21 days before Streptococcus pneumoniae infection exhibited...
Overproduction of proinflammatory cytokines is characteristic of hemophagocytic syndrome (HPS), a highly lethal inflammatory disease. Peripheral blood monocytes include two distinct subpopulations according to surface antigen expression: a major type, CD14+/CD16− (classical monocytes), and a minor type, CD14+/CD16bright (proinflammatory monocytes). Among peripheral blood monocytes from HPS patients,...
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