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Erectile dysfunction (ED) is a worldwide problem threatens men's health. The incidence of ED in diabetic patients is higher than that in the healthy population. The incidence of peripheral and autonomic neuropathy is significantly higher in diabetic patients than in normal men. Vasomotor nerves play an important role in the regulation of erectile function. Degeneration of autonomic and sensory nerves...
To investigate the relationship between hypoxia and epididymal dysfunction and the mechanism of epididymal dysfunction in rats with left‐side varicocele, a total of 45 male Wistar rats were randomly divided into three groups in average. The expression of hypoxia‐inducible factor‐1α (HIF‐1α) was detected by Western blot and immunohistochemical analysis respectively. HIF‐1α was expressed in the experimental...
The damaging effect of hyperlipidaemia on testicular structure was determined, and the influence of melatonin was evaluated in testicular damage related to hyperlipidaemia. Hyperlipidaemia was induced in ApoE‐knockout C57BL/6J male mice fed with high‐fat diet alone (group A), or with high‐fat diet and melatonin (group B). Six ApoE wild‐type C57BL/6J male mice were fed with normal diet, served as controls...
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