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Discovered gene regulation networks are very helpful to predict unknown gene functions. Microarray gene expression data reveals activation and deactivation relations among genes. There are evidences showing that multiple time units delay exist in a gene regulation process. Association rule mining technique is very suitable for finding regulation relations among genes. However, current association...
Proteins play an important role in the function of organism. The protein-protein interaction brings the interaction of cells and executes functions of physiology. A protein complex is either permanent or transient. Proteins recognize each other by forming transient complexes. In order to predict protein-protein recognition, we study the residue distribution on the binding sites of the two contacting...
Transforming sequences into numeric feature vectors is a promising method in bio-sequence similarity search. The process of transformation will lost some information of the origin sequence. In order to improve the accuracy, weight assignment can be used. Based on this notion, we proposed an adaptive weighting distance which is based on feature vector that contains three groups of features: count,...
Similarity search in biology sequences has received substantial attention in the past decade. Sequence alignment is the essential task for similar sequence search in bioinformatics. The biological sequence databases have getting larger in past decade, finding sequences similar to the query sequence is a time consuming task. By transforming sequences into numeric feature vectors, we can quickly filter...
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