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To follow-up previous studies highlighting a possible role for cytochrome P450, family 2, subfamily C, 19 (CYP2C19) in susceptibility to endometriosis by searching for additional variants in the CYP2C19 gene that may be associated with the disease.Case-control study.Academic research.The cases comprised 2,271 women with surgically confirmed endometriosis; the controls comprised 939 women with self-report...
To refine a previously reported linkage peak for endometriosis on chromosome 10q26, and conduct follow-up analyses and a fine-mapping association study across the region to identify new candidate genes for endometriosis.Case-control study.Academic research.Cases = 3,223 women with surgically confirmed endometriosis; controls = 1,190 women without endometriosis and 7,060 population samples.Analysis...
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