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Aim
Irisin, a novel myocyte‐secreted hormone mediating beneficial effects of exercise on metabolism, is supposed to be an ideal therapeutic target for metabolic disorders such as obesity and diabetes. Here, we investigated the potential effects of metformin and glibenclamide, two antidiabetic medicines, on irisin release in mouse.
Methods
Wild‐type and diabetic obese db/db mice were administrated...
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