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Introduction: Cardiovascular heart disease (CHD) is the commonest cause of death in postmenopausal women. Hormone replacement therapy (HRT) is protective against the development of CHD; it is estimated that approximately 50% of the protective effect of HRT is attributable to the beneficial effect of estrogen on lipoprotein profile. Hepatic lipase (HL) is an enzyme, that is thought to be under sex...
Introduction: Insulin plays an important role in the regulation of ovarian androgen production. Hyperinsulinaemia is a common finding in women with PCOS and is thought to contribute to the hyperandrogenaemia in these patients. Some recent studies using metformin have reported success in treating hyperinsulinaemia in these patients. The objective of the study was to examine the effect of metformin...
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