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Considerable controversy exists regarding myocardial damage in diabetes mellitus (DM) as little clinical data is available in prediabetic patients. The OLETF rats have been established as an animal model of DM. In this strain, hyperglycemia is evident spontaneously from 14 weeks of age. We performed transmittal pulsed Doppler examination in 20 OLETF and 20 non-DM rats (CONT). All were male and...
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