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The studies aimed to induce endotoxin tolerance in horses and to evaluate this state with regard to clinical observations. Investigations involved 8 clinically healthy mares subjected to 4 iv. injections with 0.1 μg/kg b.w. doses of LPS from E. coli each; the three fast doses (LPS-1, LPS-2, and LPS-3) were given daily whereas the fourth injection (LPS-4) was performed one week after LPS-3. Rectal...
The aim of the study was to determine the influence of various doses of lipopolysaccharides (LPS) on the phagocytic activity of neutrophils in 12 clinically healthy mares. Three mares were regarded as the controls; the experimental groups consisted of the remaining animals divided into 3 groups of 3 mares each. All experimental animals were treated with intravenous infusion at doses of 0.02, 0.05,...
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