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Molecular imaging allows for the visualization of changes at the cellular level in diseases such as cancer. A successful molecular imaging agent must rely on disease-selective targets and ligands that specifically interact with those targets. Unfortunately, the translation of novel target-specific ligands into the clinic has been frustratingly slow with limitations including the complex design and...
This paper presents the design of a low-noise multi-channel front-end readout chip integrated with a high-resolution TDC. It is foreseen to be used as front-end readout electronics of Avalanche Photo Diodes (APD) dedicated to a small animal Positron Emission Tomography (PET) system. The architecture of the chip is depicted. Two prototype chips, a ten-channel front-end chip and a three-channel high-resolution...
In this paper, a new maximum a posterior(MAP) method for PET image reconstruction defined in wavelet domain is proposed. Compared to the conventional MAP methods with Markov Random Field (MRF) prior models, the proposed method, named WD-MAP method, has better performance in characterize both local and global feature of reconstructed image due to the wavelet transform. Wavelet packet decomposition...
In this paper, a new non-regularization method for positron emission tomography (PET) reconstruction is proposed. The proposed method is a feature-based method using Fourier-Wavelet basis. In order to obtain the reconstructions, we have to calculate the Fourier-Wavelet moment (FWM) from the measurements. To achieve this, iterative method is employed. The rotation invariance property of the proposed...
In this paper, a new non-regularization method for positron emission tomography (PET) reconstruction is proposed. The proposed method is a feature-based method using Fourier-Wavelet basis. In order to obtain the reconstructions, we have to calculate the Fourier-Wavelet moment (FWM) from the measurements. To achieve this, iterative method is employed. The rotation invariance property of the proposed...
In this paper, a new non-regularization method for positron emission tomography (PET) reconstruction is proposed. The proposed method is a feature-based method using Fourier-Wavelet basis. In order to obtain the reconstructions, we have to calculate the Fourier-Wavelet moment (FWM) from the measurements. To achieve this, iterative method is employed. The rotation invariance property of the proposed...
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