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Insect sulfakinins (SKs) are multifunctional neuropeptides structurally and functionally homologous to the mammalian gastrin/cholecystokinin (CCK). It has been proposed that SKs play a role in modulating energy management in insects by interacting with adipokinetic hormone (AKH), the principle hormone controlling insect intermediary metabolism. To exclude head factors (including AKH) that influence...
The strict control of inner mitochondrial membrane permeability and selective ion transport is essential for mitochondria functioning. Potassium ions homeostasis is an important process for mitochondrial optimal functioning. Currently we characterize mitochondrial potassium channels from one of Dictyostelium species. Preliminary experiments are focused on biophysical and pharmacological characterization...
The purpose of this study was establishing the basic energetic parameters of amoeba Acanthamoeba castellaniimitochondria respiring with malate and their response to oxidative stress caused by hydrogen peroxide in the presence of Fe2+ions. It appeared that, contrary to a previous report (Trocha LK, Stobienia O (2007) Acta Biochim Polon 54: 797), H2O2-treated mitochondria of A. Castellanii did not display...
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