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We developed a 4D SPECT image reconstruction method with respiratory motion (RM) and cardiac motion (CM) compensation, and evaluated its performance using a previously developed 4D channelized Hotelling observer (CHO) model for the task based evaluation of 4D medical images. A series of 4D XCAT (eXtended CArdiac Torso) phantoms with and without a regional CM abnormality was generated that divided...
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