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The expression of disease‐specific membrane proteins (MPs) is a crucial indicator for evaluating the onset and progression of diseases. Urinalysis of in situ MPs has the potential for point‐of‐care disease diagnostics, yet remains challenging due to the lack of molecular reporter to transform the expression information of in situ MPs into the measurable urine composition. Herein, a series of tetrahedral...
Conjugation of aptamers to homogeneous catalysts (“nucleoapzymes”), heterogeneous nanoparticle catalysts (“aptananozymes”), and photocatalysts (“photoaptazymes”) yields superior catalytic/photocatalytic hybrid nanostructures emulating functions of native enzymes and photosystems. The concentration of the substrate in proximity to the catalytic sites (“molarity effect”) or spatial concentration of...