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Few reports analyze the incidence and clinical outcome of invasive fungal disease (IFD) in patients with newly diagnosed acute myeloid leukemia (AML) undergoing intensive chemotherapy, and thus the impact of different antifungal prophylactic regimens remains unclear. We analyze the incidence and clinical outcome of IFD in a large series of adult AML patients undergoing front-line intensive induction...
Background
Recently, we reported a simple prognostic score for post‐engraftment invasive fungal disease (IFD) obtained in 404 adult allogeneic hematopoietic stem cell transplant (alloSCT) (training cohort).
Objectives
We aim to validate this score in an external cohort assessing the 1‐year cumulative incidence (CI) of post‐engraftment IFD. Additionally, we analyse the type of IFD and incidence...
Objective
Characteristics and risk factors (RFs) of invasive fungal disease (IFD) have been little studied in the setting of umbilical cord blood transplantation (UCBT).
Method
We retrospectively included 205 single‐unit myeloablative UCBT recipients with a median follow‐up of 64 months.
Results
Fifty‐six episodes of IFD were observed in 48 patients (23%) at a median time of 123 days after stem...
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