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Regulatory sequence detection is a critical facet for understanding the cell mechanisms in order to coordinate the response to stimuli. Protein synthesis involves the binding of a transcription factor to specific sequences in a process related to the gene expression initiation. A characteristic of this binding process is that the same factor binds with different sequences placed along all genome....
During the process of protein synthesis, transcription of DNA to messenger RNA starts with the binding of the transcription factors to the promoter. One of the issues on the prediction of transcription factor binding is that sequences corresponding to the binding present variability. In this manuscript a method for the detection of binding site is proposed, based on a parametric uncertainty measurement...
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