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An approach for reducing toxicity and enhancing therapeutic potential of supramolecular polyamine phosphate nanoparticles (PANs) through PEGylation of polyamines before their assembly into nanoparticles is presented here. It is shown that the number of polyethylene glycol (PEG) chains for polyamine largely influence physico‐chemical properties of PANs and their biological endpoints. Poly(allylamine...
Polyamine Phosphate Nanoparticles
In article number 2102211, Sergio Enrique Moya and co‐workers present supramolecular polyamine phosphate nanoparticles (PANs) assembled from polyamines modified with polyethylene glycol (PEG) that vary size and charge depending on the number of PEG molecules per polyamine. PEGylated PANs with 10 PEG chains per polyamine display a core shell structure and show a longer...
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