The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Previous studies demonstrate that drug addiction can share the neural circuits in the brain with normal learning and memory. Re-exposure to drug-associated contexts, one way to retrieve the drug-associated memory, can trigger strong psychic craving and even relapse in addicts after prolonged abstinence. The ventromedial prefrontal cortex (vmPFC) has been shown to be involved in time-dependent reinstatement...
Emerging evidence indicates that metabotropic glutamate receptor 5 (mGluR5) critically modulates drug and drug‐related behaviors. However, the role of mGluR5 in the opiate‐induced contextual memory remains unclear. Here, we found that microinfusion of the mGluR5 antagonist 3‐((2‐Methyl‐1,3‐thiazol‐4‐yl)ethynyl)pyridine (MTEP) into the nucleus accumbens (NAc) shell, but not into the core, significantly...
Previous studies suggested that electroacupuncture (EA) can suppress opioid dependence by the release of endogenous opioid peptides. To explore the site of action and the receptors involved, we tried to inject highly specific agonists for μ-, δ- and κ-opioid receptors into the CNS to test whether it can suppress morphine-induced conditioned place preference (CPP) in the rat. Male Sprague–Dawley rats...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.